Infections after Transrectal Prostate Biopsy: Report of Fourteen Cases

Abstract

Objective: After prostate biopsy, serious and life-threatening infections of resistant strains can develop and therefore fluoroquinolones for prophylaxis is widely used. This study aimed to examine infections in patients undergoing transrectal prostate biopsy with quinolone prophylaxis and to review the articles reported in this respect. Patients and Methods: In this study, 14 cases who followed for the development of infection after transrectal ultrasonography guided prostate biopsy between the years 2005-2010 at the Department of Infectious Diseases and Clinical Microbiology of Haydarpasa Numune Training and Research Hospital were retrospectively evaluated.
Results: Ten patients (%71.4) developed sepsis, 3 patients (21.4%) urinary tract infection (UTI), and 1 patient (7.1%) acute bacterial prostatitis. In seven out of 14 patients (50%) bacteria growth was in blood culture, in 12 patients (85.7%) was in urine and in 5 patients (35.7%) was in both. E. coli was identified as the causative agent in all of the cases being the rate of extended spectrum of β-lactamases (ESBL) in E. coli strains was 42.8%, quinolone resistance 92.8 %.
Conclusion: This study suggested that fluoroquinolone resistant E. coli should be considered as an important causative agent in infections after transrectal prostate biopsy.