Toxicological Profile of Homosalate as Cosmetic Ingredients"

Abstract

 UV filters are widely used in many cosmetic products. They are added in order to protect from acute (sunburn-photo-ageing) or chronic (skin cancer) toxic effects of sunlight exposure. Although, acute and subchronic toxicity of these compounds is considered to be rather low, in the long-term exposure can cause some problems such as effects on reproductions, ontogeny, endocrine diseases and photoallergic reactions. In addition, the bioaccumulation of these the lipophilic chemicals in wildlife and human oes not seem to be considered in earlier publised toxicity studies. Homosalate (HMS) is a member of the UV filters. HMS has many industrial uses, as a vehicle for fragrance and cosmetic ingredients like sunscreen agent, ultraviolet light absorber. There are some studies regarding hormone-disrupting properties of homosalate. The aim of mini review was to collect data about toxicological effects on animal, human and aquatic biota, including studies the variety routes of exposure, and the risk assessment of usage of HMS as cosmetic ingredients